Project 1: Engineering autologous dermo-epidermal skin grafts

Our goal is to develop autologous dermo-epidermal skin composites (full thickness skin analogues) that can be used clinically to cover skin defects of any origin in one single surgical intervention. To achieve that we are testing different biodegradable matrices which serve as scaffolds with regard to their population by keratinocytes, melanocytes, endothelial cells and fibroblasts.