Project 7: Clinical Phase I and Phase II trials
After more than 11 years of research the Tissue Biology Research Unit (TBRU) of the Department of Surgery of the Children's Hospital in Zurich has come up with new skin grafts for Regenerative and Transplantation Medicine. The complex, bioengineered skin grafts resemble the properties of normal human skin as closely as possible. The close collaboration between the TBRU and the Pediatric Burn Center of the Department of Surgery of the Children's Hospital in Zurich made it possible that the above-mentioned skin grafts can be transplanted in just one surgical intervention. The new skin grafts are intended to be applied in clinical disciplines, such as Burn and Plastic Surgery and Dermatology, in Zurich and in Europe. The development of the grafts was, and is, based on findings gained by the knowledge and methods of basic research in cell and molecular biology. The Clinical Trials Phase I started in 2014 by the EuroSkinGraft, EU FP7 Consortium (coordinated by the TBRU) and the Clinical Research Priority Program (CRPP) of the University of Zurich and in close collaboration with the Pediatric Burn Center, the Clinical Trial Center (CTC) in Zurich, and the Swiss Center for Regenerative Medicine (SCRM) in Zurich.